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Introducing iTIVA: Your Ultimate Pharmacokinetic / Pharmacodynamic Simulation App

Are you a medical professional looking to enhance precision and efficiency in drug administration while expanding your knowledge in pharmacokinetics? Look no further than iTIVA, the leading pharmacokinetic/pharmacodynamic simulation application designed to revolutionize the way you estimate drug concentrations in plasma and optimize infusion schemes!

Key Features:

• Accurate Drug Concentration Estimation:
Harness the power of cutting-edge mathematical models to estimate drug concentrations in plasma. iTIVA offers an extensive library of 28 drugs and 69 pharmacokinetic models, empowering you to control anesthesia IV drugs like an expert.

• Target Controlled Infusion (TCI) Simulation:
Take control of TCI pumps like never before! iTIVA simulates TCI pump behavior, allowing you to calculate infusion schemes to attain and maintain desired target concentrations in plasma or effect site. It's like having a reliable assistant right at your fingertips.

• Comprehensive Drug Library:
From Remifentanil, Propofol to Heparin and beyond, iTIVA boasts an impressive range of 28 drugs to cater to your unique needs.

(Remifentanil, Fentanyl, Sufentanil, Alfentanil, Hydromorphone, Morphine, Ketamine, Procaine, Lidocaine, Propofol, Etomidate, Dexmedetomidine, Midazolam, Remimazolam, Thiopental, Atracurium, Cisatracurium, Rocuronium, Vecuronium, Sugammadex, Tranexamic, Magnesium sulfate, Diazepam, Heparin and Protamine)

• Explore Drug Interactions:
With 69 pharmacokinetic models and 10 pharmacodynamic models at your disposal, iTIVA facilitates in-depth exploration of drug interactions.

• MAC Age Calculation:
Quickly determine end-tidal (Et) concentration for Isoflurane, Sevoflurane, and Desflurane using the Mapleson equation. No more guesswork – iTIVA streamlines the process for you.

• Intraoperative Milestones & Case Sharing:
Record crucial intraoperative milestones and effortlessly share cases with colleagues using QR codes. Collaboration has never been this seamless!

• Save and Run Multiple Simulations:
Save your simulation cases for future review or run multiple simulations simultaneously. iTIVA adapts to your workflow and maximizes efficiency.

• Excel Data Export:
All recorded information can be conveniently exported as an Excel file. Stay organized and analyze your data with ease.

iTIVA's yearly subscription is available for US$9,99/year. 
• The subscription will be charged to iTunes Account at confirmation of purchase
• Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period
• The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal
• Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase
• Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable

More details can be found here
iTIVA Privacy Policy: https://itiva.co/privacy.html
Terms and Conditions: http://itiva.co/terms.html

Introducing iTIVA: Your Ultimate Pharmacokinetic / Pharmacodynamic Simulation App

Are you a medical professional looking to enhance precision and efficiency in drug administration while expanding your knowledge in pharmacokinetics? Look no further than iTIVA, the leading pharmacokinetic/pharmacodynamic simulation application designed to revolutionize the way you estimate drug concentrations in plasma and optimize infusion schemes!

Key Features:

• Accurate Drug Concentration Estimation:
Harness the power of cutting-edge mathematical models to estimate drug concentrations in plasma. iTIVA offers an extensive library of 28 drugs and 69 pharmacokinetic models, empowering you to control anesthesia IV drugs like an expert.

• Target Controlled Infusion (TCI) Simulation:
Take control of TCI pumps like never before! iTIVA simulates TCI pump behavior, allowing you to calculate infusion schemes to attain and maintain desired target concentrations in plasma or effect site. It's like having a reliable assistant right at your fingertips.

• Comprehensive Drug Library:
From Remifentanil, Propofol to Heparin and beyond, iTIVA boasts an impressive range of 28 drugs to cater to your unique needs.

(Remifentanil, Fentanyl, Sufentanil, Alfentanil, Hydromorphone, Morphine, Ketamine, Procaine, Lidocaine, Propofol, Etomidate, Dexmedetomidine, Midazolam, Remimazolam, Thiopental, Atracurium, Cisatracurium, Rocuronium, Vecuronium, Sugammadex, Tranexamic, Magnesium sulfate, Diazepam, Heparin and Protamine)

• Explore Drug Interactions:
With 69 pharmacokinetic models and 10 pharmacodynamic models at your disposal, iTIVA facilitates in-depth exploration of drug interactions.

• MAC Age Calculation:
Quickly determine end-tidal (Et) concentration for Isoflurane, Sevoflurane, and Desflurane using the Mapleson equation. No more guesswork – iTIVA streamlines the process for you.

• Intraoperative Milestones & Case Sharing:
Record crucial intraoperative milestones and effortlessly share cases with colleagues using QR codes. Collaboration has never been this seamless!

• Save and Run Multiple Simulations:
Save your simulation cases for future review or run multiple simulations simultaneously. iTIVA adapts to your workflow and maximizes efficiency.

• Excel Data Export:
All recorded information can be conveniently exported as an Excel file. Stay organized and analyze your data with ease.

iTIVA's yearly subscription is available for US$9,99/year. 
• The subscription will be charged to iTunes Account at confirmation of purchase
• Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period
• The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal
• Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase
• Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable

More details can be found here
iTIVA Privacy Policy: https://itiva.co/privacy.html
Terms and Conditions: http://itiva.co/terms.html

Introducing iTIVA: Your Ultimate Pharmacokinetic / Pharmacodynamic Simulation App

Are you a medical professional looking to enhance precision and efficiency in drug administration while expanding your knowledge in pharmacokinetics? Look no further than iTIVA, the leading pharmacokinetic/pharmacodynamic simulation application designed to revolutionize the way you estimate drug concentrations in plasma and optimize infusion schemes!

Key Features:

• Accurate Drug Concentration Estimation:
Harness the power of cutting-edge mathematical models to estimate drug concentrations in plasma. iTIVA offers an extensive library of 28 drugs and 69 pharmacokinetic models, empowering you to control anesthesia IV drugs like an expert.

• Target Controlled Infusion (TCI) Simulation:
Take control of TCI pumps like never before! iTIVA simulates TCI pump behavior, allowing you to calculate infusion schemes to attain and maintain desired target concentrations in plasma or effect site. It's like having a reliable assistant right at your fingertips.

• Comprehensive Drug Library:
From Remifentanil, Propofol to Heparin and beyond, iTIVA boasts an impressive range of 28 drugs to cater to your unique needs.

(Remifentanil, Fentanyl, Sufentanil, Alfentanil, Hydromorphone, Morphine, Ketamine, Procaine, Lidocaine, Propofol, Etomidate, Dexmedetomidine, Midazolam, Remimazolam, Thiopental, Atracurium, Cisatracurium, Rocuronium, Vecuronium, Sugammadex, Tranexamic, Magnesium sulfate, Diazepam, Heparin and Protamine)

• Explore Drug Interactions:
With 69 pharmacokinetic models and 10 pharmacodynamic models at your disposal, iTIVA facilitates in-depth exploration of drug interactions.

• MAC Age Calculation:
Quickly determine end-tidal (Et) concentration for Isoflurane, Sevoflurane, and Desflurane using the Mapleson equation. No more guesswork – iTIVA streamlines the process for you.

• Intraoperative Milestones & Case Sharing:
Record crucial intraoperative milestones and effortlessly share cases with colleagues using QR codes. Collaboration has never been this seamless!

• Save and Run Multiple Simulations:
Save your simulation cases for future review or run multiple simulations simultaneously. iTIVA adapts to your workflow and maximizes efficiency.

• Excel Data Export:
All recorded information can be conveniently exported as an Excel file. Stay organized and analyze your data with ease.

iTIVA's yearly subscription is available for US$9,99/year. 
• The subscription will be charged to iTunes Account at confirmation of purchase
• Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period
• The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal
• Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase
• Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable

More details can be found here
iTIVA Privacy Policy: https://itiva.co/privacy.html
Terms and Conditions: http://itiva.co/terms.html

Introducing iTIVA: Your Ultimate Pharmacokinetic / Pharmacodynamic Simulation App

Are you a medical professional looking to enhance precision and efficiency in drug administration while expanding your knowledge in pharmacokinetics? Look no further than iTIVA, the leading pharmacokinetic/pharmacodynamic simulation application designed to revolutionize the way you estimate drug concentrations in plasma and optimize infusion schemes!

Key Features:

• Accurate Drug Concentration Estimation:
Harness the power of cutting-edge mathematical models to estimate drug concentrations in plasma. iTIVA offers an extensive library of 28 drugs and 69 pharmacokinetic models, empowering you to control anesthesia IV drugs like an expert.

• Target Controlled Infusion (TCI) Simulation:
Take control of TCI pumps like never before! iTIVA expertly simulates TCI pump behavior, allowing you to calculate infusion schemes to attain and maintain desired target concentrations in plasma or effect site. It's like having a reliable assistant right at your fingertips.

• Comprehensive Drug Library:
From Remifentanil, Propofol to Heparin and beyond, iTIVA boasts an impressive range of 28 drugs to cater to your unique needs.

(Remifentanil, Fentanyl, Sufentanil, Alfentanil, Hydromorphone, Morphine, Ketamine, Procaine, Lidocaine, Propofol, Etomidate, Dexmedetomidine, Midazolam, Remimazolam, Thiopental, Atracurium, Cisatracurium, Rocuronium, Vecuronium, Sugammadex, Tranexamic, Magnesium sulfate, Diazepam, Heparin and Protamine)

• Explore Drug Interactions:
With 69 pharmacokinetic models and 9 pharmacodynamic models at your disposal, iTIVA facilitates in-depth exploration of drug interactions.

• MAC Age Calculation:
Quickly determine end-tidal (Et) concentration for Isoflurane, Sevoflurane, and Desflurane using the Mapleson equation. No more guesswork – iTIVA streamlines the process for you.

• Intraoperative Milestones & Case Sharing:
Record crucial intraoperative milestones and effortlessly share cases with colleagues using QR codes. Collaboration has never been this seamless!

• Save and Run Multiple Simulations:
Save your simulation cases for future review or run multiple simulations simultaneously. iTIVA adapts to your workflow and maximizes efficiency.

• Excel Data Export:
All recorded information can be conveniently exported as an Excel file. Stay organized and analyze your data with ease.

iTIVA's yearly subscription is available for US$9,99/year. 
• The subscription will be charged to iTunes Account at confirmation of purchase
• Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period
• The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal
• Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase
• Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable

More details can be found here
iTIVA Privacy Policy: https://itiva.co/privacy.html
Terms and Conditions: http://itiva.co/terms.html

Introducing iTIVA: Your Ultimate Pharmacokinetic / Pharmacodynamic Simulation App

Are you a medical professional looking to enhance precision and efficiency in drug administration while expanding your knowledge in pharmacokinetics? Look no further than iTIVA, the leading pharmacokinetic/pharmacodynamic simulation application designed to revolutionize the way you estimate drug concentrations in plasma and optimize infusion schemes!

Key Features:

• Accurate Drug Concentration Estimation:
Harness the power of cutting-edge mathematical models to estimate drug concentrations in plasma. iTIVA offers an extensive library of 27 drugs and 68 pharmacokinetic models, empowering you to control anesthesia IV drugs like an expert.

• Target Controlled Infusion (TCI) Simulation:
Take control of TCI pumps like never before! iTIVA expertly simulates TCI pump behavior, allowing you to calculate infusion schemes to attain and maintain desired target concentrations in plasma or effect site. It's like having a reliable assistant right at your fingertips.

• Comprehensive Drug Library:
From Remifentanil, Propofol to Heparin and beyond, iTIVA boasts an impressive range of 27 drugs to cater to your unique needs.

(Remifentanil, Fentanyl, Sufentanil, Alfentanil, Hydromorphone, Morphine, Ketamine, Procaine, Lidocaine, Propofol, Etomidate, Dexmedetomidine, Midazolam, Remimazolam, Thiopental, Atracurium, Cisatracurium, Rocuronium, Vecuronium, Tranexamic, Magnesium sulfate, Diazepam, Heparin and Protamine)

• Explore Drug Interactions:
With 68 pharmacokinetic models and 9 pharmacodynamic models at your disposal, iTIVA facilitates in-depth exploration of drug interactions.

• MAC Age Calculation:
Quickly determine end-tidal (Et) concentration for Isoflurane, Sevoflurane, and Desflurane using the Mapleson equation. No more guesswork – iTIVA streamlines the process for you.

• Intraoperative Milestones & Case Sharing:
Record crucial intraoperative milestones and effortlessly share cases with colleagues using QR codes. Collaboration has never been this seamless!

• Save and Run Multiple Simulations:
Save your simulation cases for future review or run multiple simulations simultaneously. iTIVA adapts to your workflow and maximizes efficiency.

• Excel Data Export:
All recorded information can be conveniently exported as an Excel file. Stay organized and analyze your data with ease.

iTIVA's yearly subscription is available for US$9,99/year. 
• The subscription will be charged to iTunes Account at confirmation of purchase
• Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period
• The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal
• Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase
• Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable

More details can be found here
iTIVA Privacy Policy: https://itiva.co/privacy.html
Terms and Conditions: http://itiva.co/terms.html

iTIVA is a pharmacokinetic/pharmacodynamic simulation application that estimates the concentration of drugs in plasma using mathematical models. It also simulates the behavior of a TCI (Target Controlled Infusion) pump, which calculates an infusion scheme to reach and maintain a set target concentration, either in plasma or effect site. These schemes can be implemented in volumetric infusion pumps and guided using pharmacokinetic models for "manual TCI" or target guided infusions.

iTIVA includes a library with 27 drugs, 68 pharmacokinetic models, and 9 pharmacodynamic models to explore drug interactions, which are updated continuously with a yearly subscription. The app also calculates the end-tidal (Et) concentration for a set MAC age for Isoflurane, Sevoflurane, and Desflurane, using the Mapleson equation.

- Remifentanil (ULTIVA)
- Fentanyl

- Sufentanil

- Alfentanil

- Hydromorphone
- Morphine
- Ketamine
- Procaine
- Lidocaine

- Propofol
 (DIPRIVAN)
- Etomidate
- Dexmedetomidine (PRECEDEX)
- Midazolam

- Remimazolam
- Thiopental
- Atracurium
- Cisatracurium
- Rocuronium
- Vecuronium
- Tranexamic

- Magnesium sulfate
- Diazepam
- Heparin - ACT estimation
- Protamine

Other features of the app include the ability to record intraoperative milestones, share cases with colleagues using QR codes, and save simulation cases for future review or to run multiple simulations at once. Additionally, all recorded information can be exported as an Excel file.

To access additional features, users can subscribe to iTIVA yearly*. This optional paid subscription service provides access to new PK/PD models as they become available in the literature, the ability to simulate up to 7 drugs at a time, unlimited simulations without time restrictions, and 24-hour support. Users can also request the inclusion of new models.

--------
*iTIVA full access for a year

Additional features are available when you subscribe to iTIVA yearly, this optional paid subscription service funds the app’s development and allows full access to the main features of this App:
- Access to new PK / PD models published in the literature that are updated as they become available.
- Ask to include new models
- Simulates up to 7 drug drugs at a time
- Unlimited simulations without time restriction
- Export your case data to an XLS file
- 24 hrs support

iTIVA's yearly subscription is available for US$9,99/year. The subscription will be charged to iTunes Account at confirmation of purchase
• Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period
• The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal
• Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase
• Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable

More details can be found here
iTIVA Privacy Policy: https://itiva.co/privacy.html
Terms and Conditions: http://itiva.co/terms.html

iTIVA is a pharmacokinetic/pharmacodynamic simulation application that estimates the concentration of drugs in plasma using mathematical models. It also simulates the behavior of a TCI (Target Controlled Infusion) pump, which calculates an infusion scheme to reach and maintain a set target concentration, either in plasma or effect site. These schemes can be implemented in volumetric infusion pumps and guided using pharmacokinetic models for "manual TCI" or target guided infusions.

iTIVA includes a library with 27 drugs, 68 pharmacokinetic models, and 9 pharmacodynamic models to explore drug interactions, which are updated continuously with a yearly subscription. The app also calculates the end-tidal (Et) concentration for a set MAC age for Isoflurane, Sevoflurane, and Desflurane, using the Mapleson equation.

- Remifentanil (ULTIVA)
- Fentanyl

- Sufentanil

- Alfentanil

- Hydromorphone
- Morphine
- Ketamine
- Procaine
- Lidocaine

- Propofol
 (DIPRIVAN)
- Etomidate
- Dexmedetomidine (PRECEDEX)
- Midazolam

- Remimazolam
- Thiopental
- Atracurium
- Cisatracurium
- Rocuronium
- Vecuronium
- Tranexamic

- Magnesium sulfate
- Diazepam
- Heparin - ACT estimation
- Protamine

Other features of the app include the ability to record intraoperative milestones, share cases with colleagues using QR codes, and save simulation cases for future review or to run multiple simulations at once. Additionally, all recorded information can be exported as an Excel file.

To access additional features, users can subscribe to iTIVA yearly*. This optional paid subscription service provides access to new PK/PD models as they become available in the literature, the ability to simulate up to 7 drugs at a time, unlimited simulations without time restrictions, and 24-hour support. Users can also request the inclusion of new models.

--------
*iTIVA full access for a year

Additional features are available when you subscribe to iTIVA yearly, this optional paid subscription service funds the app’s development and allows full access to the main features of this App:
- Access to new PK / PD models published in the literature that are updated as they become available.
- Ask to include new models
- Simulates up to 7 drug drugs at a time
- Unlimited simulations without time restriction
- Export your case data to an XLS file
- 24 hrs support

iTIVA's yearly subscription is available for US$9,99/year. The subscription will be charged to iTunes Account at confirmation of purchase
• Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period
• The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal
• Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase
• Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable

More details can be found here
iTIVA Privacy Policy: https://itiva.co/privacy.html
Terms and Conditions: http://itiva.co/terms.html

iTIVA is a pharmacokinetic/pharmacodynamic simulation application that estimates the plasma concentration of drugs based on mathematical models and simulates the behavior of a TCI (Target Controlled Infusion) pump, calculating an infusion scheme to reach and maintain a set target concentration, either in plasma or effect site. These schemes can be implemented in volumetric infusion pumps and be guided using pharmacokinetic models, to make "manual TCI" or target guided infusions.

Pharmacokinetic models

iTIVA includes a library with 27 drugs, more than 67 pharmacokinetic models and 9 pharmacodynamic models to explore drug interactions, that are updated continuously when you subscribe*:

- Remifentanil (ULTIVA)
- Fentanyl

- Sufentanil

- Alfentanil

- Hydromorphone
- Morphine
- Ketamine
- Procaine
- Lidocaine

- Propofol
 (DIPRIVAN)
- Etomidate
- Dexmedetomidine (PRECEDEX)
- Midazolam

- Remimazolam
- Thiopental
- Atracurium
- Cisatracurium
- Rocuronium
- Vecuronium
- Tranexamic

- Magnesium sulfate
- Diazepam
- Heparin - ACT estimation
- Protamine

This app also calculates the end-tidal (Et) concentration for a set MAC age for Isoflurane, Sevoflurane, and Desflurane, using the Mapleson equation.

- Record intraoperative milestones (like unconsciousness, BIS value, etc..)
- Share your case with other colleagues using QR codes
- Save your simulation cases to review them later, share with colleagues (e-mail, WhatsApp or AirDrop) or run multiple simulations at time.
- Export all recorded information as an excel file

--------
*iTIVA full access for a year

Additional features are available when you subscribe to iTIVA yearly, this optional paid subscription service funds the app’s development and allows full access to the main features of this App:
- Access to new PK / PD models published in the literature that are updated as they become available.
- Ask to include new models
- Simulates up to 7 drug drugs at a time
- Unlimited simulations without time restriction
- Export your case data to an XLS file
- 24 hrs support

iTIVA's yearly subscription is available for US$9,99/year. The subscription will be charged to iTunes Account at confirmation of purchase
• Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period
• The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal
• Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase
• Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable

More details can be found here
iTIVA Privacy Policy: https://itiva.co/privacy.html
Terms and Conditions: http://itiva.co/terms.html